This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be (...) preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

Faces are highly salient objects for humans, providing identity- and emotion-related information—basic cues for mastering social interactions. Despite extensive research on the recognition of facia...

Sören Kierkegaard gilt als „Vater der Existenzphilosophie“. Durch Schwermut bzw. Melancholie „zuinnerst in die Frage nach sich selber geworfen“ (Wilhelm Weischedel), habe er das Thema der Existenz philosophisch entdeckt. Tatsächlich, dies versucht der vorliegende Artikel zu zeigen, war Kierkegaard traumatisiert. Ein Trauma ist, anders als Schwermut oder Melancholie (modern gesprochen: Depression), keine psychische Erkrankung, sondern eine „gesunde Reaktion auf eine kranke Situation“, die die Verarbeitungsmöglichkeiten des Individuums überfordert. Das Selbst wird dabei gefährdet oder gar zerstört. Der Versuch, „für sich (...) selbst durchsichtig zu werden“ ( Joakim Garff ), auf den Kierkegaards Denken hinauslief, kann entsprechend als philosophische Traumabewältigung gelten – jedoch nicht so, dass dabei ein psychisches Problem, sondern Existenzielles verarbeitet wird. Denn: Im Trauma erfährt man die „Abgründigkeit des Seins“, es führt „direkt in die Tiefenstruktur der Existenz“ (A. Längle). Dass Kierkegaard dabei Halt in der Transzendenz gefunden hat, erweist sich als immanent konsequent. (shrink)

Gutes und Guter, Leben, Leib, Tugend - in diesem Band werden die Vortrage der ersten vier Symposien der Mainz Moral Meetings aus den Jahren 2009-2011 zu diesen Themen zusammengefasst. Ein interdisziplinarer Zugang durch Bibelwissenschaft, Judaistik, Altphilologie, Philosophie, Patristik, Systematische Theologie und weiteren Disziplinen eroffnet einen Blick auf die ethischen Normen des fruhen Christentums. Die Autoren der Beitrage fragen nach den Moglichkeiten von Norm und Normbegrundung einer fruhchristlichen Ethik in ausgewahlten Bereichen sowohl im Kontext antiker Philosophie als auch in gegenwartiger Verantwortung. (...) Mit Beitragen von: Jochen Althoff, Frederick D. Aquino, Wilhelm Blumer, Maximilian Forschner, Christian Hengstermann, Christoph Horn, Friedrich W. Horn, David Horrell, Manfred Lang, Sebastian Moll, Maren Niehoff, Jorg Roder, Eckart David Schmidt, Nikolaus Schneider, Lorenzo Scornaienchi, Notger Slenczka, Mira Stare, Gerd Theissen, Ulrich Volp, Jan G. van der Watt, Werner Zager, Ruben Zimmermann. (shrink)

Frontmatter -- Vorwort -- Inhalt -- 1. Teil Klassische Positionen -- Natürliche Freiheit / Locke, John -- Freiheit und praktische Vernunft / Kant, Immanuel -- Bürgerliche Freiheit / Mill, John Stuart -- Natürliche Freiheit, moralische Einschränkungen und der Staat / Nozick, Robert -- Kant's Theory of Justice / Pogge, Thomas W. -- Morality and the Liberal Ideal / Sandel, Michael J. -- Freiheit im Liberalismus und bei Marx -- 2. Teil Zeitgenössische Positionen -- Zwei Freiheitsbegriffe / Berlin, Isaiah -- Liberalism (...) / Dworkin, Ronald -- Gleiche Freiheit für alle / Rawls, John -- Theoretical Foundations of Liberalism / Waldron, Jeremy -- Defending Liberalism / Galston, William -- Liberalism and the Art of Separation / Walzer, Michael -- Der Gedanke eines übergreifenden Konsenses / Rawls, John -- 3. Teil Rechtsphilosophische Aspekte -- Between Utility and Rights / Hart, H. L. A. -- The Utilitarian Logic of Liberalism / Hardin, Russell -- Freiheit, Normen und operatives Gerichtsverfahren / Roberts, Julian -- 4. Teil Postmoderne Freiheit -- The Subject and Power / Foucault, Michel --,Nachmetaphysische Ethik' oder: die Freiheit, seine Moral selbst zu wählen / Scheit, Herbert -- Die Kontingenz eines liberalen Gemeinwesens / Rorty, Richard -- 5. Teil Entscheidungstheoretische Aspekte -- Individualrechte ernst - aber nicht unangemessen ernst genommen / Trapp, Rainer Werner -- Grundlinien einer Theorie gesellschaftlicher Freiheit / Koller, Peter -- Positionen und Rechte: Drei Lösungen des Liberalen Paradoxons / Kern, Lucian / Nida-Rümelin, Julian -- Zur Bedeutung von Freiheitsrechten für die moralische Beurteilung kollektiver Entscheidungen / Nida-Rümelin, Martine -- Quellennachweise -- Backmatter. (shrink)

Pinder, Wilhelm, Kunstgeschichte nach generationen.--Neumann, Friedrich. Die gliederung der deutschen literaturgeschichte.--Wirth, Wilhelm. Die zeitwahrnehmung.--Petsch, Robert. Gedanken über den aufbau des dramas.--Litt, Theodor. Person und sache im philosophischen denken.--Bülow, Friedrich. Johannes Volkelt und die Hegelsche philosophie.--Everth, Erich. Volkelts ästhetische grundgedanken.--Driesch, Hans. Johannes Volkelts erkenntnislehre und metaphysik.--Schingnitz, Werner. Kontemplation als wurzel von philosophie und kunst.--Körte, Alfred. Das schlusskapitel von Xenophons Symposion.--Studniczka, Franz. Ein neues bildnis des Sokrates.

Big data biology—bioinformatics, computational biology, systems biology (including ‘omics’), and synthetic biology—raises a number of issues for the philosophy of science. This article deals with several such: Is data-intensive biology a new kind of science, presumably post-reductionistic? To what extent is big data biology data-driven? Can data ‘speak for themselves?’ I discuss these issues by way of a reflection on Carl Woese’s worry that “a society that permits biology to become an engineering discipline, that allows that science to slip into (...) the role of changing the living world without trying to understand it, is a danger to itself.” And I argue that scientific perspectivism, a philosophical stance represented prominently by Giere, Van Fraassen, and Wimsatt, according to which science cannot as a matter of principle transcend our human perspective, provides the best resources currently at our disposal to tackle many of the philosophical issues implied in the modeling of complex, multilevel/multiscale phenomena. (shrink)

The goal of referent tracking is to create an ever-growing pool of data relating to the entities existing in concrete spatiotemporal reality. In the context of Electronic Healthcare Records (EHRs) the relevant concrete entities are not only particular patients but also their parts, diseases, therapies, lesions, and so forth, insofar as these are salient to diagnosis and treatment. Within a referent tracking system, all such entities are referred to directly and explicitly, something which cannot be achieved when familiar concept-based systems (...) are used in what is called “clinical coding”. In this paper we describe the components of a referent tracking system in an informal way and we outline the procedures that would have to be followed by healthcare personnel in using such a system. We argue that the referent tracking paradigm can be introduced with only minor – though nevertheless ontologically important – technical changes to existing EHR infrastructures, but that it will require a radically different mindset on the part of those involved in clinical coding and terminology development from that which has prevailed hitherto. (shrink)

The first comprehensive interpretation of Nietzsche's Thus Spoke Zarathustra--an important and difficult text and the only book Nietzsche ever wrote with characters, events, setting, and a plot. Laurence Lampert's chapter-by-chapter commentary on Nietzsche's magnum opus clarifies not only Zarathustra's narrative structure but also the development of Nietzsche's thinking as a whole. "An impressive piece of scholarship. Insofar as it solves the riddle of Zarathustra in an unprecedented fashion, this study serves as an invaluable resource for all serious students of Nietzsche's (...) philosophy. Lampert's persuasive and thorough interpretation is bound to spark a revival of interest in Zarathustra and raise the standards of Nietzsche scholarship in general."--Daniel W. Conway, Review of Metaphysics "A book of scholarship, filled with passion and concern for its text."--Tracy B. Strong, Review of Politics "This is the first genuine textual commentary on Zarathustra in English, and therewith a genuine reader's guide. It makes a significant and original contribution to its field."--Werner J. Dannhauser, Cornell University "This is a very valuable and carefully wrought study of a very complex and subtle poetic-philosophical work that provides access to Nietzsche's style of presenting his thought, as well as to his passionately affirmed values. Lampert's commentary and analysis of Zarathustra is so thorough and detailed... that it is the most useful English-language companion to Nietzsche's 'edifying' and intriguing work."--Choice Selected as one of Choice's outstanding academic books for 1988. (shrink)

The objective of this paper is to refute the widely held view that in the wake of his so-called reistic turn Brentano subjected his notion of intentionality to a deep-going revision, viz., that he turned from an ontological account of the intentional object by way of identifying it with the thought-of-thing, i.e., the intentional correlate, or by way of attributing to it a peculiar sort of existence, to a non-ontological account thereof. It will be shown that neither the pre-reistic Brentano (...) espoused anything of an ontological account of the intentional object in that he both distinguished it sharply from the intentional correlate and definitely rejected the idea of there being different sorts of existence, and it will be argued that the apparently ineradicable inclination to ascribe to the pre-reistic Brentano an ontological account of the intentional object stems from ignoring the Aristotelian background of Brentano's thinking about relations. (shrink)

We performed a qualitative analysis of the Thesaurus in order to assess its conformity with principles of good practice in terminology and ontology design. We used both the on-line browsable version of the Thesaurus and its OWL-representation (version 04.08b, released on August 2, 2004), measuring each in light of the requirements put forward in relevant ISO terminology standards and in light of ontological principles advanced in the recent literature. Version 04.08b of the NCI Thesaurus suffers from the same broad range (...) of problems that have been observed in other biomedical terminologies. For its further development, we recommend the use of a more principled approach that allows the Thesaurus to be tested not just for internal consistency but also for its degree of correspondence to that part of reality which it is designed to represent. (shrink)

„Luhmann meets Nietzsche“ – Luhmann hat in seinem Werk jeden Anschein vermieden, mit Nietzsche zu tun zu haben. Das hatte Folgen: Bis heute scheut Nietzsche, wer Luhmann kennt, und auch wer Nietzsche kennt, scheut Luhmann. Ihre Orientierungen scheinen füreinander abwegig zu sein: Philosophie hier, Soziologie dort, hier aphoristischer und bilderreicher Stil, dort hoch komplexe, konsequent gepflegte Theorie und zwischen beiden ein Jahrhundert, das die Welt von Grund auf verändert hat. Doch Luhmann könnte für das 21. Jahrhundert entfaltet haben, was Nietzsche (...) im 19. Jahrhundert gedacht hat. Seine soziologische Systemtheorie bewegt sich in philosophischen Dimensionen, und Nietzsche hatte bereits soziologische Perspektiven auf die Gesellschaft entwickelt, die Soziologen vom Fach bald dankbar aufgenommen haben. Nietzsche und Luhmann zusammen lassen mit ihren radikal neuen Ansätzen die meisten Philosophien und Soziologien des 20. Jahrhunderts buchstäblich alt aussehen. Sie könnten Wegbereiter einer Philosophie für das 21. Jahrhundert sein, für eine gelassene Orientierung im verstörenden Nihilismus. Wenn man sie einander begegnen lässt. (shrink)

DieVorlesung über Moralphilosophie aus den 1770er Jahren ist eine wichtige Erläuterung und Ergänzung zur Grundlegung der Metaphysik der Sittenvon 1785. Die Neuedition der so genannten Menzer-Vorlesung präsentiert diese Vorlesung auf dem aktuellen Stand der Forschung. Zugrunde gelegt ist die Nachschrift Kaehler, die seit 1997 zum Kant-Archiv in Marburg gehört. Abgeglichen ist der Text mit mehreren Handschriften des Archivs der Berlin-Bandenburgischen Akademie der Wissenschaften und der Staatsbibliothek Berlin. Ein Anhang mit textkritischem Apparat und Erläuterungen zu Literatur und Personen sowie eine Einleitung (...) von Manfred Kühn erschließen die Vorlesung für alle, die sich für die Kant'sche Philosophie der Ethik interessieren. (shrink)

Driven by technological innovations, newborn screening (NBS) panels have been expanded and the development of genomic NBS pilot programs is rapidly progressing. Decisions on disease selection for NBS are still based on the Wilson and Jungner (WJ) criteria published in 1968. Despite this uniform reference, interpretation of the WJ criteria and actual disease selection for NBS programs are highly variable. A systematic literature search [PubMED search “Wilson” AND “Jungner”; last search 16.07.22] was performed to evaluate the applicability of the WJ (...) criteria for current and future NBS programs and the need for adaptation. By at least two reviewers, 105 publications (systematic literature search, N = 77; manual search, N = 28) were screened for relevant content and, finally, 38 publications were evaluated. Limited by the study design of qualitative text analysis, no statistical evaluation was performed, but a structured collection of reported aspects of criticism and proposed improvements was instead collated. This revealed a set of general limitations of the WJ criteria, such as imprecise terminology, lack of measurability and objectivity, missing pediatric focus, and absent guidance on program management. Furthermore, it unraveled specific aspects of criticism on clinical, diagnostic, therapeutic, and economical aspects. A major obstacle was found to be the incompletely understood natural history and phenotypic diversity of rare diseases prior to NBS implementation, resulting in uncertainty about case definition, risk stratification, and indications for treatment. This gap could be closed through the systematic collection and evaluation of real-world evidence on the quality, safety, and (cost-)effectiveness of NBS, as well as the long-term benefits experienced by screened individuals. An integrated NBS public health program that is designed to continuously learn would fulfil these requirements, and a multi-dimensional framework for future NBS programs integrating medical, ethical, legal, and societal perspectives is overdue. (shrink)

Electronic Health Records (EHRs) are organized around two kinds of statements: those reporting observations made, and those reporting acts performed. In neither case does the record involve any direct reference to what such statements are actually about. They record not: what is happening on the side of the patient, but rather: what is said about what is happening. While the need for a unique patient identifier is generally recognized, we argue that we should now move to an EHR regime in (...) which all clinically salient particulars – from the concrete disorder on the side of the patient and the body parts in which it occurs to the concrete treatments given – should be uniquely identified. This will allow us to achieve interoperability among different systems of records at the level where it really matters: in regard to what is happening in the real world. It will also allow us to keep track of particular disorders and of the effects of particular treatments in a precise and unambiguous way. We discuss the ontological and epistemological aspects of our claim and describe a scenario for implementation within EHR systems. (shrink)

Es wird versucht, einige Aspekte von Carnaps Werk Der logische Auflyau der Welt vor dem Hintergrund des Kantianismus zu betrachten, insbesondere die Strukturalismusthese, das Verhältnis von Gegebenem und Konstruiertem und den Wirklichkeitsbegriff; das Ergebnis geht dahin, daß sich mehr Gemeinsamkeiten mit der kantianischen Tradition zeigen als es von einem klassischen Werk des Neopositivismus zu erwarten wäre.

The paradigm of referent tracking is based on a realist presupposition which rejects so-called negative entities (congenital absent nipple, and the like) as spurious. How, then, can a referent tracking-based Electronic Health Record deal with what are standardly called ‘negative findings’? To answer this question we carried out an analysis of some 748 sentences drawn from patient charts and containing some form of negation. Our analysis shows that to deal with these sentences we need to introduce a new ontological relationship (...) between a particular and a universal, which holds when no instance of the universal has a specific qualified ontological relation with the particular. This relation is found to be able to accommodate nearly all occurrences of negative findings in the examined sample, in ways which involve no reference to negative entities. (shrink)

The goal of the OBO (Open Biomedical Ontologies) Foundry initiative is to create and maintain an evolving collection of non-overlapping interoperable ontologies that will offer unambiguous representations of the types of entities in biological and biomedical reality. These ontologies are designed to serve non-redundant annotation of data and scientific text. To achieve these ends, the Foundry imposes strict requirements upon the ontologies eligible for inclusion. While these requirements are not met by most existing biomedical terminologies, the latter may nonetheless support (...) the Foundry’s goal of consistent and non-redundant annotation if appropriate mappings of data annotated with their aid can be achieved. To construct such mappings in reliable fashion, however, it is necessary to analyze terminological resources from an ontologically realistic perspective in such a way as to identify the exact import of the ‘concepts’ and associated terms which they contain. We propose a framework for such analysis that is designed to maximize the degree to which legacy terminologies and the data coded with their aid can be successfully used for information-driven clinical and translational research. (shrink)

Elvira Schnabel; Wittgenstein on Rules: what follows and what does not, Journal of Philosophy of Education, Volume 25, Issue 1, 30 May 2006, Pages 83–94, https.

This is the second of two articles in which I reflect on “generalized Darwinism” as currently discussed in evolutionary economics. In the companion article (Callebaut, Biol Theory 6. doi: 10.1007/s13752-013-0086-2, 2011, this issue) I approached evolutionary economics from the naturalistic perspectives of evolutionary epistemology and the philosophy of biology, contrasted evolutionary economists’ cautious generalizations of Darwinism with “imperialistic” proposals to unify the behavioral sciences, and discussed the continued resistance to biological ideas in the social sciences. Here I assess Generalized Darwinism (...) as propounded by Geoffrey Hodgson, Thorbjørn Knudsen, and others, concentrating on the roles of theory and model building in science (and the roles of analogy and metaphor therein), generative replication, and the relation between selection and self-organization. I then point to advances in current biology that promise to be more fruitful as sources of inspiration for evolutionary economics than the project to generalize Darwinism in its current, “hardened Modern Synthesis” form; and I draw some conclusions. (shrink)

Review text: "Aufs Ganze besehen präsentiert St. einen ambitionierten Entwurf, der Verschiedenstes auf eine Kernstruktur zu beziehen vermag. Vieles ist bedenkenswert und bietet Anlass, über Grundsätzliches und weitgespannte Zusammenhänge nachzusinnen."Stefan Berg in: Zeitschrift für evangelische Ethik 2/2010 "Ein stattlicher Band von einem renommierten Verlag... "In: Neue Zürcher Zeitung, 29.9.2008.

Es wird versucht, einige Aspekte von Carnaps Werk Der logische Auflyau der Welt vor dem Hintergrund des Kantianismus zu betrachten, insbesondere die Strukturalismusthese, das Verhältnis von Gegebenem und Konstruiertem und den Wirklichkeitsbegriff; das Ergebnis geht dahin, daß sich mehr Gemeinsamkeiten mit der kantianischen Tradition zeigen als es von einem klassischen Werk des Neopositivismus zu erwarten wäre.